闫海龙

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闫海龙

Title:教授/博导

E-mail Address:yhl198151@cqu.edu.cn

Tel.:023-65678461

个人/团队介绍

https://www.x-mol.com/groups/yan_hailong

学习工作经历

2021.1-至今        太阳集团tyc9728      经理

2019.2-至今        太阳集团tyc9728      教授/博导

2013.5-2019.2    太阳集团tyc9728      研究员/博导

2012.5-2013.4    新加坡国立大学      博士后,合作导师:Prof. Zhao Yu

2011.9-2012.3    韩国成均馆大学      博士后,合作导师:Prof. Song Choong Eui

研究领域

天然产物、药物活性分子的不对称合成

项目成果

1.国家自然科学基金优秀青年基金项目

2.中组部“万人计划”青年拔尖人才项目

3.国家自然科学基金面上项目

4.国家自然科学基金青年项目

5.重庆市重点产业共性关键技术创新专项重点研发项目

6.重庆市自然科学基金面上项目

代表性文章

1. Huang, S.; Wen, H.; Tian, Y  .; Wang, P.; Qin, W.; Yan, H*. Organocatalytic Enantioselective Construction of Chiral Azepine Skeleton Bearing Multiple-Stereogenic Elements. Angew. Chem. Int. Ed. 2021, 60, 2-10.

2. Liu, Y.; Liu, S.; Li, D.; Zhang, N.; Peng, L.; Ao, J.; Song, C. E.; Lan, Y.; Yan, H*. Kinetic Resolution of Allylic Alcohol with Chiral BINOL-Based Alkoxides: A Combination of Experimental and Theoretical Studies. J. Am. Chem. Soc. 2019, 141, 1150-1159.

3. Jia, S.; Li, S.; Liu, Y.; Qin, W.; Yan, H*. Enantioselective Control of Both Helical and Axial Stereogenic Elements though an Organocatalytic Approach. Angew. Chem. Int. Ed. 2019, 58, 18496-18501.

4. Peng, L.; Li, K.; Xie, C.; Li, S.; Xu, D.; Qin, W.; Yan, H*. Organocatalytic Asymmetric Annulation of ortho-Alkynylanilines: Synthesis of Axially Chiral Naphthyl-C2-indoles. Angew. Chem. Int. Ed. 2019, 58, 17199-17204.

5. Peng, L.; Xu, D.; Yang, X.; Tang, J.; Feng, X.; Zhang, S.; Yan, H*. Organocatalytic Asymmetric One-Step Desymmetrizing Dearomatization Reaction of Indoles : Development and Bioactivity Evaluation. Angew. Chem. Int. Ed. 2019, 58, 216-220.

6. Tan, Y.; Jia, S.; Hu, F.; Liu, Y.; Peng, L.; Li, D.; Yan, H*. Enantioselective Construction of Vicinal Diaxial Styrenes and Multiaxis System via Organocatalysis. J. Am. Chem. Soc. 2018, 140, 16893-16898.

7. Jia, S.; Chen, Z.; Zhang, N.; Tan, Y.; Liu, Y.; Deng, J.; Yan, H*. Organocatalytic Enantioselective Construction of Axially Chiral Sulfone-Containing Styrenes. J. Am. Chem. Soc. 2018, 140, 7056-7060.

8. Liu, Y.; Wu, X.; Li, S.; Xue, L.; Shan, C.; Zhao, Z.; Yan, H*. Organocatalytic Atroposelective Intramolecular [4+2] Cycloaddition : Synthesis of Axially Chiral Heterobiaryls. Angew. Chem. Int. Ed. 2018, 57, 6491-6495.

9. Tan, Yu.; Luo, S.; Li, D.; Zhang, N.; Jia, S.; Liu, Y.; Qin, W.; Yan, H*. Enantioselective Synthesis of anti-syn-Trihalides and anti-syn-anti-Tetrahalides via Asymmetric β-Elimination. J. Am. Chem. Soc. 2017, 139, 6431-6436.

10. Wu, X.; Xue, L.; Li, D.; Jia, S.; Ao, J.; Deng, J.; Yan, H*. Organocatalytic Intramolecular [4+2] Cycloaddition between In Situ Generated Vinylidene ortho-Quinone Methides and Benzofurans. Angew. Chem. Int. Ed. 2017, 56, 13722-13726.

11. Liu, Y.; Ao, J.; Paladhi, S.; Song, C. E.; Yan, H*. Organocatalytic Asymmetric Synthesis of Chiral Dioxazinanes and Dioxazepanes with in Situ Generated Nitrones via a Tandem Reaction Pathway Using a Cooperative Cation Binding Catalyst. J. Am. Chem. Soc. 2016, 138, 16486-16492.

12. Li, L.; Liu, Y.; Peng, Y.; Yu, L.; Wu, X.; Yan, H*. Kinetic Resolution of β-Sulfonyl Ketones through Enantioselective β-Elimination using a Cation-Binding Polyether Catalyst. Angew. Chem. Int. Ed. 2016, 55, 331-335.