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王鹏飞Title：副研究员/硕士生导师 E-mail Address：wangpf@cqu.edu.cn Tel.： |
- 个人/团队介绍
- 学习工作经历
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2023.09-至今 太阳成集团，太阳集团tyc9728，副研究员
2020.03-2023.08 太阳成集团，太阳集团tyc9728，弘深青年教师
2017.06-2019.11 哥本哈根大学，药理药设学院，药物化学，博士后
2012.09-2017.06 南京大学，生命科学学院，生物学，硕博连读
- 研究领域
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小分子药物的理性设计、合成与评价研究
- 项目成果
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主持国家自然科学基金青年基金项目“基于天然产物Odilorhabdins的新型抗生素的设计、合成与生物活性评价”一项，编号22001025
- 代表性文章
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1. Wang, P. F., Jensen, A. A., Bunch, L. From Methaqualone and Beyond: Structure–Activity Relationship of 6-, 7-, and 8-Substituted 2, 3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA Receptors. ACS Chemical Neuroscience, 2020, 11(24), 4362-4375.
2. Wang, P. F., Qiu, H. Y., He, Y., Zhu, H. L. Cyclin-dependent Kinase 4/6 Inhibitors for Cancer Therapy: A Patent Review (2015–2019). Expert Opinion on Therapeutic Patents, 2020, 30(10), 795-805.
3. Wang, P. F., Qiu, H. Y., Zhu, H. L. A Patent Review of BRAF Inhibitors: 2013-2018. Expert Opinion on Therapeutic Patents, 2019, 29(8), 595-603.
4. Wang, P. F., Wang, Z. F., Qiu, H. Y., Huang, Y., Hu, H. M., Wang, Z. C., Zhu, H. L. Identification and Biological Evaluation of Novel Type II B‐RafV600E Inhibitors. ChemMedChem, 2018, 13(23), 2558-2566.
5. Wang, P. F., Zhang, Y. J., Wang, D., Hu, H. M., Wang, Z. C., Xu, C., Zhu, H. L. Design, Synthesis, and Biological Evaluation of New B-RafV600E Kinase Inhibitors. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2372-2380.
6. Wang, P. F., Qiu, H. Y., Wang, Z. F., Zhang, Y. J., Wang, Z. C., Li, D. D., Zhu, H. L. Identification of Novel B-RafV600E Inhibitors Employing FBDD Strategy. Biochemical Pharmacology, 2017, 132, 63-76.
