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邱寒月Title：助理研究员 E-mail Address：hanyue.qiu@cqu.edu.cn Tel.： |
- 个人/团队介绍
- 学习工作经历
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2020.09-至今 太阳成集团，太阳集团tyc9728，弘深青年教师
2017.11-2020.06 南京大学，生命科学学院，药学，博士后
2017.11-2020.06 哥本哈根大学，药理药设学院，药物化学，博士后
2012.09-2017.09 南京大学，生命科学学院，生物学，硕博连读
- 研究领域
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具有药物活性的天然产物的理性改造
- 项目成果
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主持国家自然科学基金青年基金项目“吲哚生物碱koumine的全合成及基于理性设计的药物化学研究”一项，编号22101037
- 代表性文章
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1. Han-Yue Qiu†, Jiang-Yan Fu†, Min-Kai Yang†, Hong-Wei Han, Peng-Fei Wang, Ya-Han Zhang, Hong-Yan Lin, Cheng-Yi Tang, Jin-Liang Qi, Rong-Wu Yang, Gui-Hua Lu, Xiao-Ming Wang*, Hai-Liang Zhu*, Yong-Hua Yang*. Identification of New Shikonin Derivatives as STAT3 SH2 Domain Inhibitors. Biochemical Pharmacology, 2017, 146: 74-86.
2. Han-Yue Qiu†, Peng-Fei Wang†, Zhen Li, Jun-Ting Ma, Xiao-Ming Wang*, Yong-Hua Yang*, Hai-Liang Zhu*. Synthesis of dihydropyrazole sulphonamide derivatives that act as anti-cancer agents through COX-2 inhibition. Pharmacological research, 2016, 104: 86-96.
3. Han-Yue Qiu†, Xiang Zhu†, Yue-Lin Luo, Hong-Yan Lin, Cheng-Yi Tang, Jin-Liang Qi, Yan-Jun Pang, Rong-Wu Yang, Gui-Hua Lu*, Xiao-Ming Wang*, Yong-Hua Yang*. Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain. Scientific reports, 2017, 7: 2863.
4. Han-Yue Qiu, Fang Wang, Xue Wang, Wen-Xue Sun, Jin-Liang Qi, Yan-Jun Pang, Rong-Wu Yang, Gui-Hua Lu*, Xiao-Ming Wang*, Yong-Hua Yang*. Design, Synthesis, and Biological Evaluation of Chalcone‐Containing Shikonin Derivatives as Inhibitors of Tubulin Polymerization. ChemMedChem, 2017, 12(5): 399-406.
