Xuli Feng

The Feng Research Group focuses on developing new methods and strategies to deliver functional genes or proteins for the treatment of various human illnesses such as cancer, infectious diseases, and metabolic diseases.

2013-Present: Professor, School of Pharmacy, Innovative Drug Research Centre, Chongqing University, Chongqing, China

2012-2013: Postdoctoral Fellow, Department of Bioengineering, University of California, Berkeley, USA

2011.7-2011.12: Postdoctoral Fellow, Department of Biomedical Engineering, Georgia Institute of Technology, USA

2006–2011: Ph.D., Institute of Chemistry Chinese Academy of Sciences, Beijing, China

2001–2005: B.S., Department of Chemistry, Shaanxi Normal University, Shanxi, China

1. Transportation of medicinal proteins

2. Transportation of new gene preparations

Awards and Honors:

Won the third prize of "Outstanding Papers of the First Sichuan-Chongqing Science and Technology Academic Conference" (2020) and the third prize of "Chongqing 2020 General Undergraduate College Teacher Teaching Innovation Competition".

Grants:

1. Small circular nucleotide probe with greater tension and preparation method and application. (CN201610019655.2)

2. Amphiphilic nano medicine and its preparation method and application. (CN201710397627.9)

Fundings:

1. National Natural Science Foundation of China（21877010）

2. National Natural Science Foundation of China（21773268）

3. National Natural Science Foundation of China (21472090)

4. Fundamental Research Funds for the Central Universities (2019CDYGYB006)

5. The Startup Funding of Chongqing University (0236011104419)

6. Fundamental Research Funds for Central Universities (CDJZR 14465502, 02131438004)

1.  Lan Yang, Xiao He, Zhiying Zeng, Jiakun Tang, Dongmei Qi, Huijie Ma,Hui Chen*, Xinghai Ning* and Xuli Feng*. Clickable amino acid tuned self-assembly of a nucleus-selective multi-component nanoplatform for synergistic cancer therapy. Chem. Sci. 2021, 12, 8394-8400.

2.  Jiakun Tang, Ye Liu, Dongmei Qi, Lan Yang, Hui Chen*, Chenhui Wang*, Xuli Feng*. Nucleus-Targeted Delivery of Multi-Protein Self-Assembly for Combined Anticancer Therapy. Small 2021, 17, 2101219.

3.  Zhiying Zeng, Xiao He, Changying Li, Shan Lin, Hui Chen*, Libing Liu*, Xuli Feng*. Oral delivery of antioxidant enzymes for effective treatment of inflammatory disease. Biomaterials 2021, 271, 120753.

4.  Xiao He, Lan Yang, Hang Su, Shan Lin, Dongmei Qi, Hui Chen*, Yunfeng Qu*, Libing Liu*, Xuli Feng*. Clickable amino acid derivative tuned self-assembly of antigen and adjuvant for effective immunotherapy. J. Control. Release 2021, 337, 306-316.

5.  Xiao He, Qipeng Long, Zhiying Zeng, Lan Yang, Yaqin Tang, Xuli Feng*. Simple and Efficient Targeted Intracellular Protein Delivery with Self‐Assembled Nanovehicles for Effective Cancer Therapy. Adv. Func. Mater. 2019, 29, 1906187.

6.  Zhiying Zeng, Dongmei Qi, Lan Yang, Jin Liu, Yaqin Tang, Hui Chen, Xuli Feng*.Stimuli-responsive self-assembled dendrimers for oral protein delivery. J. Control. Release 2019, 315, 206-213.

7.  Tingting Wang, Yaqin Tang, Xiao He, Ju Yan, Chenhui Wang,* and Xuli Feng*.Self-Assembled Raspberry-Like Core/Satellite Nanoparticles for Anti-Inflammatory Protein Delivery. ACS Appl. Mater. Interfaces 2017, 9, 6902−6907.

8.  Yaqin Tang, Ziying Zeng, Xiao He, Tingting Wang, Xinghai Ning,* and Xuli Feng*. SiRNA Crosslinked Nanoparticles for the Treatment of Inflammation-induced Liver Injury. Adv. Sci. 2016, 4, 1600228.

9.  Yaqin Tang, Xiao He, Zhenxia Zhou, Jiakun Tang, Rong Guo and Xuli Feng*. Highly sensitive and selective miRNA detection based on a closed ring probe and multiple signal amplification. Chem. Commun. 2016, 52, 13905-13908.

10.  Ming Chen, Yaqin Tang, TingtingWang, Qipeng Long, Ziying Zeng, Houwen Chen, Xuli Feng*. Enhanced gene delivery of low molecular weight PEI by flower-like ZnO microparticles. Mater. Sci. Eng. C 2016, 69, 1367-1372.

11.  Yaqin Tang, Tingting Wang, Ming Chen, Xiao He, Xiaohuan Qu, Xuli Feng*. Tension promoted circular probe for highly selective microRNA detection and imaging. Biosens. Bioelectron. 2016, 85, 151-156.

12.  Ming Chen, Zhiying Zeng, Xiaohuan Qu, Yaqin Tang, Qipeng Long, Xuli Feng*. Biocompatible anionic polyelectrolyte for improved liposome based gene transfection. Int. J. Pharm. 2015, 490, 173-179.